In the preparation process of drug raw materials and intermediates, the uneven particle size distribution of API particles and the difference in powder fineness often lead to the loss of product value and even the risk of market rejection. If the plant fiber content in the drug powder exceeds the standard, it will limit its value-added potential. In addition, the particle size of pills is different and sticky, and there are nearly a thousand types. Therefore, efficient and accurate sieving machine in pharmaceutical industry have become important equipment for pharmaceutical companies to improve product quality and production efficiency.

API conveying and sieving machine in pharmaceutical industry

Active pharmaceutical ingredients (APIs) are the chemical-based compounds that have produced mainly in the countries the USA, Europe, China, and India. APIs have pharmacological activity mainly used with combination of other ingredients to diagnose, cure, mitigate, and treat the disease.

Project Overview

This project comes from the needs of large pharmaceutical companies for API screening. They want to introduce advanced pharmaceutical sieving machine and technology to solve the problems of unqualified powder grade and dust overflow in the screening process of API powder.

Challenge

High screening accuracy requirements: The screening of API powder needs to achieve extremely high accuracy to ensure that the quality of the drug meets the standard.
Easy to block: APIs have high viscosity and strong adsorption, which can easily cause blockage or damage during the screening process, especially for fine raw materials such as capsule micro-pellets.
Dust control is difficult: Dust is easily generated during the screening process, and effective measures must be taken to prevent dust from spreading and protect the production environment and personnel health.
Production efficiency needs to be improved: While ensuring the screening quality, the screening efficiency needs to be improved to meet the needs of large-scale production.

Solutions

The project uses rotary vibro sifter, dust-free feeding station, vacuum feeder, and other equipment to build an efficient and environmentally friendly API screening production line to meet the company’s 500kg/h processing capacity requirements and achieve fine grading of API powder within the range of 16-250 mesh.

Screening material: API powder
Processing capacity: 500kg/h
Screening mesh: 16-250 mesh
Material: 304
Equipment: rotary vibro sifter, dust-free feeding station, vacuum feeder

Features of drug screening production line

Rotary vibro sifter: Advanced screening technology and equipment are used to ensure the fine grading of API powder and improve screening accuracy and efficiency.
Equipped with dust-free feeding station: Dust generation and spillage are effectively controlled to protect the production environment and personnel health through the application of dust-free feeding station and vacuum feeder.
Introducing vacuum feeder: Automatic feeding and screening of APIs are realized, manual operation is reduced, and production automation is improved.
Flexible and adjustable: The screening mesh can be adjusted according to actual needs to meet the production requirements of different drugs.
Easy to maintain: The equipment structure is reasonably designed, easy to clean and maintain, and maintenance costs are reduced.

Outcome

According to customer feedback, the pharmaceutical screening production line not only solves the problems of unqualified powder grade and dust spillage but also shortens the screening time and greatly improves production efficiency.